Leukodystrophy hub
Leukodystrophy, also called "the leukodystrophies," refers to a group of genetic disorders that are characterized by the imperfect growth or development of the white matter or myelin sheath covering nerve fibers in the brain. Specific leukodystrophies include metachromatic leukodystrophy, Krabbe leukodystrophy, adrenoleukodystrophy, Pelizaeus-Merzbacher disease, Canavan disease, Alexander disease, Zellweger syndrome, Refsum disease, and cerebrotendinous xanthomatosis. The most common signs seen in most leukodystrophies include gradual changes in an infant or child who previously appeared well. Changes may appear in body tone, movements, gait, speech, ability to eat, vision, hearing, behavior, memory, or thought processes. The symptoms, which vary according to the specific type of leukodystrophy, may be difficult to recognize in the early stages of the disease.
Overviews - Full text articles - Diagnosis & Treatment - Clinical trials
NINDS Leukodystrophy Information Page - by The National Institute of Neurological Disorders and Stroke, National Institutes of Health.
Metachromatic leukodystrophy - by MEDLINEplus.
Adrenal Leukodystrophy (ALD) - by Mike Rubin, M.D.
Metachromatic Leukodystrophy of the Brain - by Margaret Grunnet, M.D.
The Nosology and Etiology of Leukodystrophies of Unknown Cause
Leukodystrophy by Charles E. Kahn, Jr., MD., Medical College of Wisconsin
What is Leukodystrophy? - from Miramar College, San Diego, California.
NINDS Metachromatic Leukodystrophy Information Page - by The National Institute of Neurological Disorders and Stroke, National Institutes of Health.
Globoid Cell Leukodystrophy - by .F. Fletcher, DVM, PhD and H.J. Kurtz, DVM, PhD, Departments of Anatomy, and Pathology and Parasitology, College of Veterinary Medicine, University of Minnesota, St. Paul, Minn.
Globoid Cell Leukodystrophy (GCL) - by Westie Health Concerns.
Case reports
Childhood Leukodystrophy Presenting As Secondary Bipolar Disorder - by Harpreet. S. Duggal, Vinod K. Sinha & S. Haque Nizamie.
Directories - Hubs - Web forums
Leukodystrophy from The Family Village
Leukodystrophy Menu - a webforum to discuss and comment on leukodystrophy by the Department of Neurology at Massachusetts General Hospital.
Leukodystrophy by HealthlinkUSA
Leukodystrophy by Debra Collins, M.S. CGC, Genetic Counselor, University of Kansas Medical Center
FAQ
Metachromatic Leukodystrophy: Research Into Developing Therapies - from the University of Pittsburgh Department of Human Genetics.
Globoid cell leukodystrophy - by Canine Inherited Disorders Database.
Abstracts
A Rare Form of Adult Onset Leukodystrophy: Orthochromatic Leukodystrophy with Pigmented Glia - by P. Shannon, J.R. Wherrett and S. Nag.
Krabbe's Leukodystrophy- Between Hesitation and Diagnosis - by Zaprianov, Z; Staribratova, D; Ivanov, I, Higher Medical Institute, Bulgaria.
Leukodystrophy and oculocutaneous albinism in a child with a 11q14 deletion identified by FISH - by D. Lacombe, C. Goizet, I. Coupry, P. Verin, B. Mortemousque, L. Taine, B. Arveiler.
Globoid cell leukodystrophy in Cairn and West Highland white terriers - by DA Wenger, T Victoria, MA Rafi, P Luzi, MT Vanier, C Vite, DF Patterson, and MH Haskins.
Personal stories and experiences
One Man's Viewpoint - by Thomas P. Nolan.
Foundations - Associations - Support groups
United Leukodystrophy Foundation
Australian Leukodystrophy Support
Metachromatic Leukodystrophy (LDM) - from Mauro Baschirotto Institute for Rare Diseases (B.I.R.D).
News archives - News releases
New specialty clinic for leukodystrophy metabolic disorders
Last modified: October 3, 2001. Admin© 2023 Projectlinks Database